A transparent look at what shapes the price of regenerative medicine, our published package prices, how costs in the United States and Mexico compare, and what is included when you travel with Gold Standard Regenerative. Stem cell therapy is investigational and not FDA-approved.
There is no single sticker price for stem cell therapy. Because regenerative medicine is investigational and not FDA-approved, it is generally not covered by insurance, and pricing is not standardized the way a routine medical billing code might be. What you pay reflects the biology of your treatment, the protocol the treating provider designs, and where the procedure is performed.
That is why any honest answer begins with an evaluation. A physician reviews your history, imaging, and goals before a protocol, and therefore a price, can be put in front of you. The package prices on this page are ranges, not quotes. A medical evaluation is required before any estimate is provided.
This guide is designed to help you understand what drives cost so you can compare options thoughtfully, ask better questions, and avoid choosing a provider on price alone.
Three packages, priced as ranges. Every package includes premium accommodation and airport and border transportation; you book your own flight to San Diego. Where your price falls within a range depends on the dose and the number of areas your physician recommends.
Treatment areas: Knee · Shoulder · Back · Neck
A focused starting protocol
25M–75M MSC$3,744–$5,544
Our recommended protocol
100M–125M MSC + exosomes$6,444–$7,544
Our most comprehensive protocol
150M–300M MSC + exosomes$8,444–$12,444
Prices are in U.S. dollars. Your final price depends on your physician’s evaluation, including the cell dose and the number of areas treated. Results vary from person to person, and no specific outcome is guaranteed. Stem cell and exosome therapies are investigational and not FDA-approved. MSC means mesenchymal stem cells; M means million cells.
Consultation
Virtual consultation and a personalized plan.
San Diego
You book your flight to San Diego; we coordinate ground transport, lodging, and care from there.
Tijuana
Private transportation across the border.
Treatment
Your personalized protocol at a COFEPRIS-licensed partner clinic.
Recover
Most patients stay one night in a premium hotel.
Home
Transportation back to San Diego for your flight home.
A few factors explain most of the difference between one quote and another. The treating provider weighs all of them when designing a protocol.
Mesenchymal stem cells, exosomes, and other preparations are produced and screened differently. Sourcing from GMP-certified tissue banks with rigorous testing affects cost.
Higher cell counts and larger doses generally cost more. The dose the treating provider selects depends on your condition and the area being treated.
Treating one knee is different from treating both knees, a shoulder, or a systemic protocol. More target areas typically means a higher total.
Single-visit injections differ from multi-modality or combination protocols that layer several therapies over time. Complexity influences price.
Ultrasound or image-guided placement adds precision and may add cost compared with a landmark-only injection.
Structured follow-up and monitoring are part of responsible care. Programs that include longer follow-up may be priced accordingly.
Cost differences between countries are real, but they are not the whole story. Here is a neutral, factual way to think about them.
Varies by provider
In the United States, many advanced cell therapy protocols have not completed the FDA approval process, so they are not offered at U.S. clinics. Where related regenerative procedures are available, they are typically quoted per treatment area and paid out of pocket. Figures vary widely by provider and region.
GSR packages: $3,744–$12,444
In Mexico, COFEPRIS-licensed clinics may offer protocols that are not yet available in the U.S. Differences in facility, regulatory, and operational costs can make pricing more accessible. Lower cost does not mean lower quality, and it should never replace careful review of a clinic's licensing and a physician's credentials.
Gold Standard Regenerative package prices are shown in U.S. dollars; see the packages above. Your final price depends on your physician’s evaluation, and results vary. Compare providers on licensing, physician credentials, cell sourcing, and follow-up care, not price alone.
Gold Standard Regenerative is a U.S. medical-concierge service. We coordinate your care with a COFEPRIS-licensed partner clinic in Tijuana, Mexico. Exact inclusions are confirmed during your consultation, and typically cover:
Not sure whether this applies to your case? Candidacy is determined by medical review of your history and imaging, not by a form. The consultation is complimentary.
See If You QualifyMost insurance plans do not cover regenerative cell therapies, because these therapies are considered investigational and are not FDA-approved. That said, many patients pay using Health Savings Account (HSA) or Flexible Spending Account (FSA) funds.
Whether HSA or FSA funds can be used depends on your plan, your administrator, and applicable tax rules. GSS does not provide tax or benefits advice and cannot determine or guarantee eligibility. Please confirm what your plan allows with your plan administrator. Full treatment costs are shared openly during your consultation, with no surprise fees.
Because pricing is evaluation-based, the most useful number is the one built for your situation. The path is simple: request a consultation, have a physician review your history and imaging, and let the clinical team outline a protocol with a personalized estimate.
Want to know what the journey looks like first? Read what to expect at your consultation, explore how stem cell therapy works, see stem cell therapy for knees in Tijuana, or, if you have been told you need surgery, review alternatives to knee replacement. When you are ready, a consultation is the next step. Evaluation is required before any estimate is provided.
Gold Standard Regenerative offers three packages for the knee, shoulder, back, or neck: Foundation ($3,744 to $5,544), Restore ($6,444 to $7,544), and Renew ($8,444 to $12,444), in U.S. dollars. Your final price depends on your physician’s evaluation, including the cell dose and the number of areas treated. Results vary.
Many advanced cell therapy protocols have not completed the FDA approval process, so they are not offered at U.S. clinics. In Mexico, COFEPRIS-licensed clinics may offer them. Price differences reflect facility, regulatory, and operational factors. Evaluate licensing and physician credentials, not price alone.
Every package includes the physician evaluation, the procedure at our COFEPRIS-licensed partner clinic in Tijuana, premium accommodation, airport and border transportation, and aftercare and follow-up. You book your own flight to San Diego. Exact inclusions are confirmed during your consultation.
Whether HSA or FSA funds can be used depends on your plan, administrator, and applicable tax rules. GSS does not provide tax advice or guarantee eligibility. Please confirm with your plan administrator.
Most insurance plans do not cover regenerative cell therapies because they are considered investigational and are not FDA-approved. Full costs are shared openly during your consultation.
Start with a consultation. After a physician reviews your history, imaging, and goals, the clinical team can outline a protocol and provide a personalized estimate. Evaluation is required before any estimate is provided.
Talk with our team, complete a medical evaluation, and receive a clear, itemized estimate built around your protocol and goals.
REQUEST AN ESTIMATE →