Gold Standard
Regenerative
Stem cell therapy targets the immune imbalance at the root of autoimmune disease, without shutting down your entire immune system the way conventional drugs do.
Autoimmune disease happens when your immune system mistakes your own tissue for a threat and attacks it. The damage depends on which tissue gets hit: joints in rheumatoid arthritis, nerve myelin in multiple sclerosis, the thyroid in Hashimoto's, the pancreas in Type 1 diabetes, or many organs at once in lupus. Stem cell therapy offers a different strategy than the immunosuppressants most patients rely on: instead of shutting the immune system down, stem cells aim to retrain it.
Mesenchymal stem cells (MSCs) are being studied for their potential to influence immune activity. Researchers are investigating whether, once infused, they may interact with sites of inflammation and release regulatory factors, but these mechanisms are not established. Any regenerative approach is intended to be used alongside, not as a replacement for, your existing medications, which should be managed only by your prescribing physician.
Standard treatments like DMARDs, biologic drugs, and corticosteroids reduce inflammation by suppressing the immune system broadly. They help, but come with infection risk, organ stress over the long term, and no path to resetting the underlying dysfunction. Stem cell therapy is an investigational, complementary approach that researchers are studying for its potential effect on immune regulation. It is not a proven treatment and is not a replacement for your prescribed care.
Research supports stem cell therapy and exosomes for several autoimmune conditions. Treatment approaches are tailored to each condition.
Rheumatoid arthritis causes immune-driven joint inflammation and progressive joint damage. Researchers are studying whether stem cells may influence inflammatory signals and immune regulation in rheumatoid arthritis. These effects are not established, and this use is investigational and not FDA-approved.
Lupus involves out-of-control immune activation that can affect many organ systems at once. Researchers are studying whether stem cell signaling may influence immune activity and inflammation, but these effects are not proven and individual responses vary. Some early studies have explored stem cell therapy in autoimmune disease; this research is preliminary, and these therapies are not FDA-approved for lupus.
Fibromyalgia and chronic inflammatory fatigue involve heightened nerve sensitivity, brain inflammation, and ongoing immune activation. Researchers are studying whether exosome-based approaches might influence inflammation in these conditions. This use is investigational, benefits are not established, and results vary.
Ankylosing spondylitis causes long-term inflammation in the spine and sacroiliac joints, which can lead to the joints fusing together over time. Researchers are studying whether stem cell protocols might influence spinal inflammation in this condition. This use is investigational, benefits are not established, and results vary.
A personalized plan built around a thorough assessment of your condition, disease activity, and goals.
The independent treating physician reviews your diagnosis, disease history, lab results, and current medications during your medical evaluation. This clinical baseline is established by the provider, not by GSS, and helps the physician determine whether you may be a candidate.
Based on your assessment, we design a customized plan using stem cell therapy, exosome therapy, or a combination. The plan takes into account your condition, current disease activity, how you have responded to past treatments, and which parts of the immune system are most involved.
Depending on your condition, stem cell therapy is delivered by IV infusion for systemic conditions or by targeted injection for joint and spinal disease. Both are outpatient procedures. All stem cell and exosome preparations come from screened, certified providers.
Any clinical follow-up, including repeat lab tests or disease-activity assessment, is conducted by the treating physician, not by GSS. We encourage you to maintain ongoing coordination with your existing rheumatologist or specialist throughout this time.
Not sure whether this applies to your case? Candidacy is determined by medical review of your history and imaging, not by a form. The consultation is complimentary.
See If You QualifyAny changes after stem cell therapy tend to occur gradually. This general timeline is illustrative only; individual experiences vary and no outcome is guaranteed.
Stem cells and exosomes begin shifting the body's inflammatory balance. Some patients notice early reductions in joint pain, fatigue, or other symptoms as inflammatory signals start to decrease.
Individual responses vary, and no outcome is guaranteed. Any changes in lab values or symptoms are assessed by the treating physician. This is not a promise of any specific result.
Individual responses vary and no outcome is guaranteed. Some patients report changes in how they feel during this period, but any changes are assessed by the treating physician.
Results vary, and no outcome is guaranteed. Any change to your medications must be decided and managed solely by your own prescribing physician. GSS does not provide medical advice or direct medication changes, and you should never stop or reduce a prescribed medication without your doctor's guidance.
Research has looked at rheumatoid arthritis, lupus, multiple sclerosis, Crohn's disease and others. Being studied is not the same as being an approved treatment, and evidence differs considerably from one condition to another.
Laboratory and clinical research describes mesenchymal stem cells as immunomodulatory, meaning they appear to influence signalling between immune cells rather than suppress the immune system broadly. How far that translates into clinical benefit in specific autoimmune diseases is not established.
No. Nothing offered here is a cure, and any clinic describing it that way is overstating what the research supports. These are investigational approaches, not curative treatments.
That is a decision for the physician managing your condition, and it should be made with them rather than independently. Bring a complete list of medications to your evaluation. Some conditions and medications make regenerative approaches unsuitable.
A physician, after reviewing your diagnosis, disease activity, medications and medical history. Certain uncontrolled conditions rule it out entirely.
Connect with our coordination team to explore whether stem cell therapy may be available for your autoimmune condition and goals through an independent provider.
CHECK IF YOU QUALIFY →Medically reviewed by Dr. Karla Chavira, MD, Regenerative Medicine Physician and CEO of CMCells (Cédula Profesional on file).
Last reviewed: July 2026